Update

Recent work has implicated autophagy in lipid processing and the cardiovascular community is buzzing with new studies on autophagy and heart disease.  For me personally heart disease, given my family history, is more likely to kill me than any neurodegenerative disease and so, I will look into the subject and add cardio-vascular diseases to the list of diseases that protein cycling might prevent.  There is a lot of literature to digest and this may take some time.